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1

Crystallization and preliminary X-ray analysis of Escherichia coli methionyl–tRNA formyltransferase

Emmanuelle Schmitt, Yves Mechulam, Marc Ruff, Andre Mitschler, Dino Moras, Sylvain Blanquet

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1996

Langue:

english

Fichier:

PDF, 274 KB

english, 1996

2

Une expérience innovante dans la prise en charge des plaies chroniques : l’Équipe Mobile Plaies et Cicatrisations du Centre Alsace

Mitschler, A., Roth, B., Michel, J.-M., Guillaume, J.-C.

Journal:

Annales de Dermatologie et de Vénéréologie

Année:

2007

Langue:

french

Fichier:

PDF, 45 KB

french, 2007

3

Ultrahigh resolution drug design I: Details of interactions in human aldose reductase–inhibitor complex at 0.66 Å

E.I. Howard, R. Sanishvili, R.E. Cachau, A. Mitschler, B. Chevrier, P. Barth, V. Lamour, M. Van Zandt, E. Sibley, C. Bon, D. Moras, T.R. Schneider, A. Joachimiak, A. Podjarny

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2004

Langue:

english

Fichier:

PDF, 577 KB

english, 2004

4

The role of general practitioners in diagnosis of cutaneous melanoma: a population-based study in France

Grange, F., Barbe, C., Mas, L., Granel-Brocard, F., Lipsker, D., Aubin, F., Velten, M., Dalac, S., Truchetet, F., Michel, C., Mitschler, A., Arnoult, G., Buemi, A., Dalle, S., Reuter, G., Bernard, P.,

Journal:

British Journal of Dermatology

Année:

2012

Langue:

english

Fichier:

PDF, 97 KB

english, 2012

5

Could Jessner’s Lymphocytic Infiltrate of the Skin Be a Dermal Variant of Lupus Erythematosus? An Analysis of 210 Cases

Lipsker, Dan, Mitschler, Audrey, Grosshans, Edouard, Cribier, Bernard

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 679 KB

english, 2006

6

Reaction of 1-alkyl-1,1'-diphosphaferrocene monoanions with acyl chlorides. Synthesis and zwitterionic structure of stable .lambda.3,.lambda.5-diphosphaferrocenes

Deschamps, Bernard, Fischer, Jean, Mathey, Francois, Mitschler, Andre, Ricard, Louis

Journal:

Organometallics

Année:

1982

Langue:

english

Fichier:

PDF, 1.15 MB

english, 1982

7

Neutron structure of type-III antifreeze protein allows the reconstruction of AFP–ice interface

Eduardo I. Howard, Matthew P. Blakeley, Michael Haertlein, Isabelle Petit- Haertlein, Andre Mitschler, Stuart J. Fisher, Alexandra Cousido- Siah, Andrés G. Salvay, Alexandre Popov, Christoph Muller- D

Journal:

Journal of Molecular Recognition

Année:

2011

Langue:

english

Fichier:

PDF, 783 KB

english, 2011

8

Peroxo and alkylperoxidic molybdenum(VI) complexes as intermediates in the epoxidation of olefins by alkyl hydroperoxides

Patrick Chaumette, Hubert Mimoun, Lucien Saussine, Jean Fischer, Andre Mitschler

Journal:

Journal of Organometallic Chemistry

Année:

1983

Langue:

english

Fichier:

PDF, 1.30 MB

english, 1983

9

Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications

Michael C. Van Zandt, Evelyn O. Sibley, Erin E. McCann, Kerry J. Combs, Brenda Flam, Diane R. Sawicki, Al Sabetta, Anne Carrington, Janet Sredy, Eduardo Howard, Andre Mitschler, Alberto D. Podjarny

Journal:

Bioorganic & Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 436 KB

english, 2004

10

A new heteronuclear cluster compound: [P(C6H5)3]2Pt2Co2(CO)3. Synthesis and crystal structure

J. Fischer, A. Mitschler, R. Weiss, J. Dehand, J.F. Nennig

Journal:

Journal of Organometallic Chemistry

Année:

1975

Langue:

english

Fichier:

PDF, 137 KB

english, 1975

11

Organometallic complexes with metal—metal bonds: XVI. Synthesis of new tri- and tetrametallic platinum-manganese complexes. Crystal structures of (OC)4Mn(μ2-PPh2)Pt(CO)(μ2-PPh2)Mn(CO)4, (OC)4Mn(μ2-PPh2)PtH(μ2-PPh2)2Mn(CO)4 and (OC)4Mn(μ2-PPh2)Pt(μ2-PPh2)2Pt(μ2-PPh2)Mn(CO)4

Pierre Braunstein, Dominique Matt, Odile Bars, Michèle Louër, Daniel Grandjean, Jean Fischer, André Mitschler

Journal:

Journal of Organometallic Chemistry

Année:

1981

Langue:

english

Fichier:

PDF, 1.95 MB

english, 1981

12

Binding of aldose reductase inhibitors: correlation of crystallographic and mass spectrometric studies

H Rogniaux, A Van Dorsselaer, P Barth, J.F Biellmann, J Barbanton, M van Zandt, B Chevrier, E Howard, A Mitschler, N Potier, L Urzhumtseva, D Moras, A Podjarny

Journal:

Journal of the American Society for Mass Spectrometry

Année:

1999

Langue:

english

Fichier:

PDF, 523 KB

english, 1999

13

Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat: Implications for the binding of cyclic imide inhibitors

Ossama El-Kabbani, Connie Darmanin, Thomas R. Schneider, Isabelle Hazemann, Federico Ruiz, Mitsuru Oka, Andrzejj Joachimiak, Clemens Schulze-Briese, Takashi Tomizaki, Andre Mitschler, Alberto Podjarny

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2004

Langue:

english

Fichier:

PDF, 482 KB

english, 2004

14

Comparison of hydrogen determination with X-ray and neutron crystallography in a human aldose reductase–inhibitor complex

M. P. Blakeley, A. Mitschler, I. Hazemann, F. Meilleur, D. A. A. Myles, A. Podjarny

Journal:

European Biophysics Journal

Année:

2006

Langue:

english

Fichier:

PDF, 521 KB

english, 2006

15

Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor

Billas, Isabelle M. L., Iwema, Thomas, Garnier, Jean-Marie, Mitschler, André, Rochel, Natacha, Moras, Dino

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 744 KB

english, 2003

16

Conformational adaptation of agonists to the human nuclear receptor RARγ

Klaholz, B.P., Renaud, J.-P., Mitschler, A., Zusi, C., Chambon, P., Gronemeyer, H., Moras, D.

Journal:

Natural Structural Biology

Année:

1998

Fichier:

PDF, 521 KB

1998

17

A Comparative Study of Lipid Compositions of Cryptosporidium parvum (Apicomplexa) and Madin-Darby Bovine Kidney Cells

RALENE R. MITSCHLER, RUTH WELTI, STEVE J. UPTON

Journal:

Journal of Eukaryotic Microbiology

Année:

1994

Langue:

english

Fichier:

PDF, 633 KB

english, 1994

18

Dicoordinated 2H-phospholes as transient intermediates in the reactions of tervalent phospholes at high temperature. One-step syntheses of 1-phosphanorbornadienes and phosphorins from phospholes

Mathey, Francois, Mercier, Francois, Charrier, Claude, Fischer, Jean, Mitschler, Andre

Journal:

Journal of the American Chemical Society

Année:

1981

Langue:

english

Fichier:

PDF, 412 KB

english, 1981

19

Crystal packing modifies ligand binding affinity: The case of aldose reductase

Alexandra Cousido-Siah, Tatiana Petrova, Isabelle Hazemann, André Mitschler, Francesc X. Ruiz, Eduardo Howard, Stephan Ginell, Cédric Atmanene, Alain Van Dorsselaer, Sarah Sanglier-Cianférani, Andrzej

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2012

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2012

20

Identification and localization of rab6, separation of rab6 from ERD2 and implications for an ‘unstacked’ Golgi, in Plasmodium falciparum

Jeffrey Van Wye, Nafisa Ghori, Paul Webster, Ralene R. Mitschler, Heidi G. Elmendorf, Kasturi Haldar

Journal:

Molecular and Biochemical Parasitology

Année:

1996

Langue:

english

Fichier:

PDF, 1.47 MB

english, 1996

21

A ‘specificity’ pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil

A Urzhumtsev, F Tête-Favier, A Mitschler, J Barbanton, P Barth, L Urzhumtseva, J-F Biellmann, AD Podjarny, D Moras

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 983 KB

english, 1997

22

Novel unusually stable peroxotitanium(IV) compounds. Molecular and crystal structure of peroxobis(picolinato)(hexamethylphosphoric triamide)titanium(IV)

Mimoun, Hubert., Postel, Michele., Casabianca, Francis., Fischer, Jean., Mitschler, Andre.

Journal:

Inorganic Chemistry

Année:

1982

Langue:

english

Fichier:

PDF, 545 KB

english, 1982

23

Structural basis for isotype selectivity of the human retinoic acid nuclear receptor

Bruno P Klaholz, André Mitschler, Dino Moras

Journal:

Journal of Molecular Biology

Année:

2000

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2000

24

Crystallization of threonyl-tRNA synthetase from Thermus thermophilus and preliminary crystallographic data

V. Cura, D. Kern, A. Mitschler, D. Moras

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 449 KB

english, 1995

25

X-Ray-Radiation-Induced Cooperative Atomic Movements in Protein

Tatiana Petrova, Vladimir Y. Lunin, Stephan Ginell, Isabelle Hazemann, Krzysztof Lazarski, André Mitschler, Alberto Podjarny, Andrzej Joachimiak

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 829 KB

english, 2009

26

Structural investigation of the ligand binding domain of the zebrafish VDR in complexes with 1α,25(OH)2D3 and Gemini: purification, crystallization and preliminary X-ray diffraction analysis

Fabrice Ciesielski, Natacha Rochel, Andre Mitschler, Alexander Kouzmenko, Dino Moras

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

2004

Langue:

english

Fichier:

PDF, 390 KB

english, 2004

27

Transmembrane Signaling across the Ligand-Gated FhuA Receptor: Crystal Structures of Free and Ferrichrome-Bound States Reveal Allosteric Changes

Kaspar P Locher, Bernard Rees, Ralf Koebnik, André Mitschler, Luc Moulinier, Jurg P Rosenbusch, Dino Moras

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 554 KB

english, 1998

28

The Crystal Structure of the Nuclear Receptor for Vitamin D Bound to Its Natural Ligand

N. Rochel, J.M. Wurtz, A. Mitschler, B. Klaholz, D. Moras

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 197 KB

english, 2000

29

Diagnosis and management of melanoma with regional lymph node metastases: a population-based study in France

C. Lévy-Sitbon, C. Barbe, F. Granel-Brocard, D. Lipsker, F. Aubin, S. Dalac, F. Truchetet, C. Michel, A. Mitschler, G. Arnoult, A. Le Clainche, S. Dalle, P. Bernard, F. Grange

Journal:

Journal of the European Academy of Dermatology and Venereology

Année:

2012

Langue:

english

Fichier:

PDF, 101 KB

english, 2012

30

Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole- N -acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications

Van Zandt, Michael C., Jones, Michael L., Gunn, David E., Geraci, Leo S., Jones, J. Howard, Sawicki, Diane R., Sredy, Janet, Jacot, Jorge L., DiCioccio, A. Thomas, Petrova, Tatiana, Mitschler, Andre,

Journal:

Journal of Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 338 KB

english, 2005

31

Electron density in bis(dicarbonyl-.pi.-cyclopentadienyliron) at liquid nitrogen temperature by x-ray and neutron diffraction

Mitschler, Andre, Rees, Bernard, Lehmann, Mogens S.

Journal:

Journal of the American Chemical Society

Année:

1978

Langue:

english

Fichier:

PDF, 937 KB

english, 1978

32

Factorizing Selectivity Determinants of Inhibitor Binding toward Aldose and Aldehyde Reductases: Structural and Thermodynamic Properties of the Aldose Reductase Mutant Leu300Pro−Fidarestat Complex

Petrova, Tatiana, Steuber, Holger, Hazemann, Isabelle, Cousido-Siah, Alexandra, Mitschler, Andre, Chung, Roland, Oka, Mitsuru, Klebe, Gerhard, El-Kabbani, Ossama, Joachimiak, Andrzej, Podjarny, Albert

Journal:

Journal of Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 254 KB

english, 2005

33

4,5-Dimethyl-2-(2-pyridyl)phosphorin as a chelating ligand. Synthesis and x-ray crystal structure analysis of (4,5-dimethyl-2-(2-pyridyl)phosphorin)tetracarbonylchromium

Breque, Anne, Santini, Catherine C., Mathey, Francois, Fischer, Jean, Mitschler, Andre

Journal:

Inorganic Chemistry

Année:

1984

Langue:

english

Fichier:

PDF, 675 KB

english, 1984

34

Structure of Aldehyde Reductase Holoenzyme in Complex with the Potent Aldose Reductase Inhibitor Fidarestat: Implications for Inhibitor Binding and Selectivity

El-Kabbani, Ossama, Carbone, Vincenzo, Darmanin, Connie, Oka, Mitsuru, Mitschler, Andre, Podjarny, Alberto, Schulze-Briese, Clemens, Chung, Roland P.-T.

Journal:

Journal of Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 285 KB

english, 2005

35

Synthesis and molecular structure of the dissymmetric molybdenum.cntdot.molybdenum compound [(.eta.5-C5H5)2Mo2(CO)3(C6H5P(OCH2CH2)NH)]: first example of direct carbonyl-substitution in bis[(.eta.5-cyclopentadienyl)dicarbonylmolybdenum]

Wachter, Joachim, Mitschler, Andre, Riess, Jean G.

Journal:

Journal of the American Chemical Society

Année:

1981

Langue:

english

Fichier:

PDF, 438 KB

english, 1981

36

Stabilization of 7-phosphanorbornadienes by complexation; X-ray crystal structure of 2,3-bis(methoxycarbonyl)-5,6-dimethyl-7-phenyl-7-phosphanorbornadiene(pentacarbonyl)-chromium

Marinetti, Angela, Mathey, Fran�ois, Fischer, Jean, Mitschler, Andr�

Journal:

Journal of the Chemical Society Chemical Communications

Année:

1982

Langue:

english

Fichier:

PDF, 264 KB

english, 1982

37

Modulation of Aldose Reductase Inhibition by Halogen Bond Tuning

Fanfrlík, Jindřich, Kolář, Michal, Kamlar, Martin, Hurný, David, Ruiz, Francesc X., Cousido-Siah, Alexandra, Mitschler, André, Řezáč, Jan, Munusamy, Elango, Lepšík, Martin, Matějíček, Pavel, Veselý, J

Journal:

ACS Chemical Biology

Année:

2013

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2013

38

Phosphaferrocenes as phosphorus ligands. Crystal and molecular structure of tetracarbonyl(3,4-dimethylphosphaferrocene-P)iron

Fischer, Jean, Mitschler, Andr�, Richard, Louis, Mathey, Francois

Journal:

Journal of the Chemical Society Dalton Transactions

Année:

1980

Langue:

english

Fichier:

PDF, 493 KB

english, 1980

39

Molecular Recognition of Agonist Ligands by RXRs

Egea, Pascal F., Mitschler, André, Moras, Dino

Journal:

Molecular Endocrinology

Année:

2002

Langue:

english

Fichier:

PDF, 732 KB

english, 2002

40

Thermal tetramerization of 1-phenyl-3,4-dimethylphosphole. An access to 2,2'-biphospholes and to 2,2'-diphosphafulvalene complexes

Mathey, Francois, Mercier, Francois, Nief, Francois, Fischer, Jean, Mitschler, Andre

Journal:

Journal of the American Chemical Society

Année:

1982

Langue:

english

Fichier:

PDF, 384 KB

english, 1982

41

Preparation of 3,3',4,4'-tetramethyl-1,1'-biphospholyl and its reactions with iron and cobalt carbonyls. Synthesis and x-ray crystal structure of a phospholyl complex with a chain of four cobalt atoms

Holand, Serge, Mathey, Francois, Fischer, Jean, Mitschler, Andre

Journal:

Organometallics

Année:

1983

Langue:

english

Fichier:

PDF, 635 KB

english, 1983

42

Diagnostic et prise en charge du mélanome avec métastases ganglionnaires régionales : une étude basée sur la population

Lévy-Sitbon, C., Barbe, C., Granel-Brocard, F., Lipsker, D., Aubin, F., Dalac, S., Truchetet, F., Michel, C., Mitschler, A., Arnoult, G., Le Clainche, A., Dalle, S., Bernard, P., Grange, F.

Journal:

Annales de Dermatologie et de Vénéréologie

Année:

2012

Langue:

french

Fichier:

PDF, 65 KB

french, 2012

43

Preliminary X-ray investigation of 70 S ribosome crystals from Thermus thermophilus

Trakhanov, Sergei, Yusupov, Marat, Shirokov, Vladimir, Garber, Marina, Mitschler, André, Ruff, Marc, Thierry, Jean-Claude, Moras, Dino

Journal:

Journal of Molecular Biology

Année:

1989

Langue:

english

Fichier:

PDF, 185 KB

english, 1989

44

Connaissance et prévention des borrélioses par piqûres de tiques

Mitschler, A., Grange, F., Lipsker, D., Jaulhac, B., Piemont, Y., Belanger, P., Pagnon, X., Mayer, O., Guillaume, J.-C.

Journal:

Annales de Dermatologie et de Vénéréologie

Année:

2004

Fichier:

PDF, 123 KB

2004

45

C22 - Caractéristiques cliniques et évolutives d’une série de malades ayant une maladie de Jessner et Kanof définie histologiquement

Mitschler, A., Grosshans, E., Cribier, B., Lipsker, D.

Journal:

Annales de Dermatologie et de Vénéréologie

Année:

2005

Langue:

french

Fichier:

PDF, 58 KB

french, 2005

46

Frataxin from Psychromonas ingrahamii as a model to study stability modulation within the CyaY protein family

Roman, Ernesto A., Faraj, Santiago E., Cousido-Siah, Alexandra, Mitschler, André, Podjarny, Alberto, Santos, Javier

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2013

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2013

47

A high resolution diffracting crystal form of the complex between yeast tRNAAsp and aspartyl-tRNA synthetase

Ruff, M., Mitschler, A., Cavarelli, J., Giege, R., Mikol, V., Thierry, J.C., Lorber, B., Moras, D.

Journal:

Journal of Molecular Biology

Année:

1988

Langue:

english

Fichier:

PDF, 247 KB

english, 1988

48

C039 - Maladie de Jessner et Kanof : entité propre ou forme clinique du lupus érythémateux ? Étude de 212 cas

Mitschler, A, Lipsker, D, Cribier, B

Journal:

Annales de Dermatologie et de Vénéréologie

Année:

2007

Langue:

french

Fichier:

PDF, 65 KB

french, 2007

49

X-ray structure of the V301L aldo–keto reductase 1B10 complexed with NADP+ and the potent aldose reductase inhibitor fidarestat: Implications for inhibitor binding and selectivity

Ruiz, Francesc Xavier, Cousido-Siah, Alexandra, Mitschler, André, Farrés, Jaume, Parés, Xavier, Podjarny, Alberto

Journal:

Chemico-Biological Interactions

Année:

2013

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2013

50

Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design

Cousido-Siah, Alexandra, Ruiz, Francesc X., Mitschler, André, Porté, Sergio, de Lera, Ángel R., Martín, María J., Manzanaro, Sonia, de la Fuente, Jesús A., Terwesten, Felix, Betz, Michael, Klebe, Gerh

Journal:

Acta Crystallographica Section D Biological Crystallography

Année:

2014

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2014